pentobarbital will minimize the extent or effect of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Influence of coadministering a robust CYP3A4 inducer with fedratinib hasn't been examined.

pentobarbital will lower the level or result of levamlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the level or influence of paclitaxel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.

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pentobarbital will lessen the level or influence of fosamprenavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will lower the level or influence of celecoxib by influencing hepatic enzyme CYP2C9/ten metabolism. Insignificant/Importance Unknown.

pentobarbital will reduce the level or effect of fentanyl transmucosal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of fentanyl with CYP3A4 inducers may lead to some decrease in fentanyl plasma concentrations, not enough efficacy or, maybe, progress of the withdrawal syndrome within a affected individual who's got produced physical dependence to fentanyl.

pentobarbital will decrease the level or influence of estradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital will lessen the level or effect of sulfamethoxazole by influencing hepatic enzyme CYP2C9/ten metabolism. Small/Significance Not known.

pentobarbital will minimize the extent or effect of bosentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.

pentobarbital will minimize the level or impact of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

pentobarbital will lower the level or result more info of siponimod by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of siponimod by using a drug that causes reasonable CYP2C9 additionally a moderate or robust CYP3A4 inducer just isn't advised.

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Contraindicated (one)pentobarbital will lessen the level or outcome of cobimetinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Steer clear of coadministration. Solid or reasonable CYP3A inducers could minimize cobimetinib systemic exposure by >80% and lower its efficacy.